What is a cell cycle non-specific drug?

Alkylating agents are generally considered to be cell cycle phase nonspecific, meaning that they kill the cell in various and multiple phases of the cell cycle. Although alkylating agents may be used for most types of cancer, they are generally of greatest value in treating slow-growing cancers.

What is non-specific chemotherapy?

Chemotherapy is non-specific. It does not target cancer cell alone but even the normal tissues as stated earlier. Targeted therapy directly attacks the cancer cell avoiding normal tissues. This is a great achievement of translational research.

Which of the following class of drugs is cell cycle non-specific and therefore can affect the cancer in any phase of the cell cycle?

Some chemotherapy medicines can kill a cell during any phase of the cell cycle. They are called cell-cycle nonspecific agents. Other chemotherapy medicines kill cancer cells only during a certain phase.

What is cell-cycle specific drugs?

Cell cycle phase specific agents act on the cells in a specific phase. They are most effective against tumours that have a large proportion of cells actively moving through the cell cycle and cycling at a fast rate.

What drug is used in chemotherapy?

Drugs in this group include 5-fluorouracil, 6-mercaptopurine, cytarabine, gemcitabine, and methotrexate, among many others. Anthracycline chemotherapy attacks the enzymes inside cancer cells’ DNA that help them divide and grow.

Are chemotherapy drugs radioactive?

Chemotherapy, or “chemo,” uses special drugs to shrink or kill cancer cells. Radiation therapy, or “radiation,” kills these cells with high-energy beams such as X-rays or protons.

How does chemotherapy related to cell cycle?

Chemotherapy works with the cell cycle Every time any new cell is formed, it goes through a usual process to become a fully functioning (or mature) cell. The process involves a series of phases and is called the cell cycle. Chemotherapy drugs target cells at different phases of the cell cycle.

What is a typical chemo cycle?

You may receive chemotherapy in cycles. A cycle is a period of chemotherapy treatment followed by a period of rest. For instance, you might receive chemotherapy every day for 1 week followed by 3 weeks with no chemotherapy. These 4 weeks make up one cycle. The rest period gives your body a chance to recover and build new healthy cells.

Which phase of the cell cycle is characterized by a non-dividing cell?

Once a cell has completed the cell cycle, it goes back into the G 1 phase and repeats the cycle again. Cells in the body can also be placed in a non-dividing state called the Gap 0 phase (G 0) at any point in their life.

How many cycles of chemotherapy are necessary?

ANSWER You may need four to eight cycles to treat your cancer. A series of cycles is called a course. Your course can take 3 to 6 months to complete — and you may need more than one course of chemo to beat the cancer.