What is the size of Vibrio cholerae?
Vibrio cholerae, a member of the family Vibrionaceae, is a facultatively anaero- bic, Gram-negative, non-spore-forming curved rod, about 1.4–2.6µm long, capable of respiratory and fermentative metabolism; it is well defined on the basis of biochemical tests and DNA homology studies (Baumann, Furniss & Lee, 1984).
How many chromosomes does cholera have?
two
cholerae has two circular chromosomes, a main chromosome (Chr1) of 3 Mbp and a secondary chromosome (Chr2) of 1 Mbp (6). Chr1 replication is initiated at an oriC-like origin, ori1, by DnaA. Chr2 has a plasmid-like origin, ori2, where replication is regulated by a Vibrio-specific factor, RctB (7).
Does cholera have DNA?
V. cholerae has two circular DNA. One DNA produces the cholera toxin (CT), a protein that causes profuse, watery diarrhea (known as “rice-water stool”). But the DNA does not directly code for the toxin as the genes for cholera toxin are carried by CTXphi (CTXφ), a temperate bacteriophage (virus).
What is unique about Vibrio cholerae?
CHARACTERISTICS: Vibrio cholerae is a gram negative, non-spore forming, curved rod that is oxidase positive(1,2,3). It is very motile and has a single polar flagellum(1). The bacterium is 1- 3 µm by 0.5-0.8 µm, is a facultative anaerobe and is part of the Vibronaceae family(1,3).
Does cholera have two chromosomes?
The bacterium Vibrio cholerae, the cause of the diarrhoeal disease cholera, has its genome divided between two chromosomes, a feature uncommon for bacteria. The two chromosomes are of different sizes and different initiator molecules control their replication independently.
How did cholera spread?
How is cholera spread? The cholera bacteria is passed through feces (poop). It is spread by eating or drinking food or water contaminated by the feces (poop) of an infected person. This occurs more often in underdeveloped countries lacking proper water supplies and sewage disposal.
What is cholera life cycle?
The life cycle of Vibrio cholerae allows the bacterium to live for years in an aquatic environment, its natural reservoir, where it survives adherent to crustaceans, algae and zooplankton. Under the appropriate environmental conditions, V. Cholerae will multiply and reinitiate the free life cycle.
How big is a Vibrio ( V ) cholerae?
V cholerae is a[& comma-shaped, gram-negative aerobic or facultatively anaerobic bacillus&] that varies in size from 1-3 µm in length by 0.5-0.8 µm in diameter (see the image below). Its
What kind of pathogenicity does V.cholerae have?
V. cholerae pathogenicity genes code for proteins directly or indirectly involved in the virulence of the bacteria. During infection, V. cholerae secretes cholera toxin, a protein that causes profuse, watery diarrhea (known as “rice-water stool”).
How does Vibrio cholerae spread from person to person?
Two samples collected from home wells around this drainage tested positive for Vibrio Cholerae. Cholera is an illness that derives from the bacteria, V. cholerae. This bacteria infects the intestine where it then causes diarrhea. This bacteria, V. cholerae can be spread by eating contaminated food or drinking contaminated water.
Who was the first person to discover cholera?
V. cholerae was first isolated as the cause of cholera in 1854 by Italian anatomist Filippo Pacini and by the Catalan Joaquim Balcells i Pascual in the same year, but their discovery was not widely known until Robert Koch, working independently 30 years later, publicized the knowledge and the means of fighting the disease.