What is drug induced lupus syndrome?

Drug-induced lupus (DIL) is an autoimmune phenomenon where a drug exposure leads to the development of systemic lupus erythematosus (SLE) like clinical features. DIL is a clear example of an environmental trigger leading to the development of lupus in a genetically susceptible individual.

What is shrinking lung syndrome?

Shrinking lung syndrome (SLS) is a rare complication of systemic lupus erythematosus (SLE) characterized by unexplained dyspnea, a restrictive pattern on pulmonary function tests, and an elevated hemidiaphragm. A total of 59 cases are reported in literature including the current case.

What is lupus pain like?

Lupus can also cause inflammation in the joints, which doctors call “inflammatory arthritis.” It can make your joints hurt and feel stiff, tender, warm, and swollen. Lupus arthritis most often affects joints that are farther from the middle of your body, like your fingers, wrists, elbows, knees, ankles, and toes.

What are the causes of Jaccoud arthropathy ( JA )?

Jaccoud arthropathy (JA), is a chronic non-erosive reversible joint disorder that may occur after repeated bouts of arthritis. It is caused by inflammation of the joint capsule and subsequent fibrotic retraction, causing ulnar deviation of the fingers, through metacarpophalangeal joint (MCP) subluxation, primarily of the ring and little-finger.

How does Jaccoud’s arthropathy relate to systemic lupus?

Classical Jaccoud’s arthropathy in a systemic lupus erythematosus patient (A, B), illustrating the reversibility of the hand deformities (C,D). Diffuse edema in the dorsum of the right hand in a case of Jaccoud’s arthropathy secondary to systemic lupus erythematosus.

How is Jaccoud’s arthropathy related to ligamentous laxity?

Jaccoud’s arthropathy has also been reported in patients without active arthritis 18). Jaccoud arthropathy is thought to be related to ligamentous laxity 19). Jaccoud’s arthropathy pathophysiology is poorly known but involves periarticular structures such as tendons and the joint capsule.

How is Jaccoud’s arthropathy different from marginal erosion?

“Hook” erosions may occur on the radial palmar aspect of the metacarpal heads and can be differentiated from the marginal erosions of rheumatoid arthritis 26). Jaccoud’s arthropathy is not associated with swelling, obliteration of joint spaces, or destruction of articular surfaces 27).