What are the congenital abnormalities associated with CMV infection?

Some babies with signs of congenital CMV infection at birth may have long-term health problems, such as: Hearing loss. Developmental and motor delay. Vision loss.

Can CMV cause intellectual disability?

Congenital cytomegalovirus (CMV) infection can cause microcephaly and result in a spectrum of neurodevelopmental disorders, such as sensorineural hearing loss (SNHL), vision loss, and intellectual impairment.

Is congenital CMV progressive?

Babies with congenital CMV may have hearing loss in one ear and may later develop hearing loss in the other ear. Progression may occur through adolescence.

How does CMV affect the brain?

CMV Encephalitis: CMV can cause damage to the brain. If it reaches the brain and the immune system cannot control it, death can occur within weeks to months. If brain damage is less severe, dementia, confusion, fever and memory problems can occur.

Is congenital CMV a disability?

CMV is a serious infection. Of newborns who are born with cCMV, up to one in five will have permanent disabilities. Hearing loss is the most common permanent disability for CMV.

What are the long term effects of cytomegalovirus?

CMV is the most common congenital infection in the U.S. Most infants will have no permanent health consequences, but a small number will have at birth or will develop long-term neurological conditions, such as hearing loss, visual impairment, seizures, or disabilities f mental or physical function.

What disease does cytomegalovirus cause?

Occasionally, CMV can cause mononucleosis or hepatitis (liver problem). People with weakened immune systems who get CMV can have more serious symptoms affecting the eyes, lungs, liver, esophagus, stomach, and intestines. Babies born with CMV can have brain, liver, spleen, lung, and growth problems.

When does congenital cytomegalovirus ( CCMV ) infection occur?

Congenital cytomegalovirus (CCMV) infection is the most common intrauterine infection in the U.S. and the most common cause of non-genetic sensorineural hearing loss in children. Most of the time, the disease is asymptomatic (85 to 90%). The symptomatic congenital disease occurs most often after primary maternal infection in pregnancy.

What are the side effects of congenital CMV infection?

Most infants with congenital CMV infection never have health problems. About 10% of infants with congenital CMV infection will have health problems that are apparent at birth, which include: Rash. Jaundice (yellowing of the skin or whites of the eyes) Microcephaly (small head) Intrauterine growth restriction (low weight)

How long does it take to diagnose congenital CMV?

Diagnosing Congenital CMV Infection. Congenital CMV infection is diagnosed by detection of CMV DNA in the urine, saliva (preferred specimens), or blood, within two to three weeks after birth. Infection cannot be diagnosed using tests that detect antibodies to CMV.

Can a congenital CMV infection cause hearing loss?

Dr Simone Walter discusses cCMV infection, cCMV-related hearing loss, and how to facilitate their detection and management in paediatric audiology. Congenital CMV (cCMV) can present with SNHL in otherwise well infants and children.