How do you infuse Zometa?

Zoledronic acid is prepared by diluting the 5-mL solution in no less than 100 mL of infusate. If necessary, the diluted infusion solution can be stored in the refrigerator for up to 24 hours, and then allowed to warm to room temperature before use.

What is zoledronic used for?

Zoledronic acid (Zometa) is used to treat high levels of calcium in the blood that may be caused by certain types of cancer.

When should Zometa be given?

The typical Zometa dosage for adults with multiple myeloma or bone metastases from solid tumors is 4 mg, given every 3 to 4 weeks. Each infusion should be given over at least 15 minutes.

What are the long term side effects of zoledronic acid?

Blurred vision or other change in vision.

decreased frequency or amount of urine.

decreased vision.

eye pain.

eye tenderness.

heavy jaw feeling.

increased blood pressure.

increased tearing.

Can you take Zometa at the same time as Reclast?

Zometa should never be given at the same time as other bisphosphonates, such as Reclast. Zometa must be administered over no faster than 15 minutes because shorter infusion times have been associated with an increased risk of renal toxicity which may progress to kidney failure.

What’s the maximum dose of Zometa you can take?

Zometa: Maximum dose: Single dose of 4 mg IV infusion over no less than 15 minutes. Comments: If serum calcium does not return to normal, retreatment should be considered after a minimum of 7 elapsed days. Use: Treatment of hypercalcemia of malignancy (albumin-corrected calcium equal 12 mg/dL or greater).

What do you need to know about Zometa prescribing information?

FULL PRESCRIBING INFORMATION 1 INDICATIONS AND USAGE 1.1 Hypercalcemia of Malignancy Zometa is indicated for the treatment of hypercalcemia of malignancy defined as an albumin-corrected calcium (cCa) of greater than or equal to 12 mg/dL [3.0 mmol/L] using the formula: cCa in mg/dL = Ca in mg/dL + 0.8 (4.0 g/dL – patient albumin [g/dL]).

What are the side effects of Zometa in HCM?

Electrolyte abnormalities, most commonly hypocalcemia, hypophosphatemia, and hypomagnesemia, can occur with bisphosphonate use. Grade 3 and Grade 4 laboratory abnormalities for serum creatinine, serum calcium, serum phosphorus, and serum magnesium observed in two clinical trials of Zometa in patients with HCM are shown in Table 5 and 6.