What class is Zofran?

5-HT3 antagonist
Ondansetron/Classification

What is the therapeutic effect of Zofran?

This medication is used alone or with other medications to prevent nausea and vomiting caused by cancer drug treatment (chemotherapy) and radiation therapy. It is also used to prevent and treat nausea and vomiting after surgery. It works by blocking one of the body’s natural substances (serotonin) that causes vomiting.

Is Zofran a serotonin antagonist?

Ondansetron is a serotonin (5HT3) receptor antagonist used for the prevention and treatment of postoperative nausea and vomiting.

Can Zofran be used for anxiety?

In some of the clinical trials, ondansetron has been reported as effective in controlling anxiety. Harmer et al. (2006) have shown that ondansetron abolishes emotions induced startle effects in humans.

Why is Zofran a controlled substance?

ZOFRAN 8 (Zofran 8 mg) There is no proven risk in humans during pregnancy. Zofran 8 mg is not a controlled substance under the Controlled Substances Act (CSA).

Does Zofran calm you?

Ondansetron (16 microg/kg twice daily) showed greater therapeutic efficacy at alleviating symptoms of overall mood disturbance, fatigue, vigor, confusion/bewilderment, and depression among EOA compared with LOA. EOA-associated improvements in mood disturbance seemed to be independent of drinking behavior.

What are the Common side effects of Zofran ODT?

Common side effects may include: 1 diarrhea or constipation; 2 headache; 3 drowsiness; or 4 tired feeling.

What are some of the uses of Zofran?

Uses for Zofran. Ondansetron injection is used to prevent the nausea and vomiting that may occur after treatment with cancer medicines (chemotherapy or radiation), including high-dose cisplatin. This medicine is also used to prevent and treat nausea and vomiting that may happen after surgery.

What to do if you have an irregular heartbeat while taking Zofran?

Seek immediate care if you experience an irregular heartbeat, shortness of breath, dizziness, or fainting while taking Zofran (ondansetron). Report any side effects you experience to the FDA MedWatch program using the information in the “Contact Us” box at the bottom of the page.

What kind of interactions are there with Zofran?

Zofran may interact with arsenic trioxide, tacrolimus, tramadol, antibiotics, antidepressants, anti- malaria medications, heart rhythm medicines, medicine to prevent or treat nausea and vomiting, medicines to treat psychiatric disorders, migraine headache medicines, narcotics, or seizure medications.